Gardasil (Human Papilloma Virus) vaccine prevents the spread of the most common types of
STD (Sexually Transmitted Diseases) and certain types of Cervical Cancer caused
by the Human Papilloma Virus. The FDA approved recommended indications are:
prevention of genital warts, cervical cancer, cervical adenocarcinoma, cervical
vulvar and vaginal intraepithelial neoplasias.
Most human papillomavirus (HPV) infections occur without incident or treatment,
but some may persist for years and eventually produce cellular abnormalities
leading to illnesses. Approximately 100 HPV types cause warts and more than
30 HPV types have been linked to cervical cancer. The most common viruses are
HPV 16 and 18, which cause more than 70% of cervical cancers.
HPV types 6 and 11 are considered low-risk carcinogenic types, but they are
responsible for 90% of genital warts. ACIP (Advisory Committee
on Immunization Practices) clinical study findings show that the HPV vaccine
was 100% effective in preventing cervical, vulva, and vaginal cancer; and 95%
effective in preventing genital warts. The vaccine does not appear
to be effective in women already exposed to HPV except for the virus types contained
in the vaccine that they are not infected with.
In the United States, approximately 10,000 women will be diagnosed with cervical
cancer each year, and an estimated 3,700 women will die from the disease. Cervical
Cancer is the 2nd leading cause of death among women in the world.
The CDC (Centers for Disease Control) recommendations for this vaccine are
only for girls and young women between the ages of
13 to 26 years of age for the prevention of sexually transmitted diseases. The
vaccine should be administered before onset of sexual
activity (before women are exposed to the viruses). It also recommends that
adolescent girls and women in this age group who are sexually active should
be vaccinated.
Abstinence or a mutually monogamous sexual relationship is the only effective
method to prevent STDs completely. In all other cases, use a latex condom.
The HPV vaccine is not a replacement for routine cervical cancer screening
or an annual gynecologic examination. It must be remembered that other types
of HPV cause cancer; therefore, annual PAP SMEARS must be continued.
HPV vaccine is a “three-dose” series vaccine administered
with 0.5 ml IM (intramuscularly) in the upper arm at 0, 2, and 6 months (or
initial shot now, then in 2 months, and final third shot at 6 months).
HPV Vaccine is manufactured by Merck & Company, Inc. under the Trade Name
of *Gardasil and is a noninfectious inactivated quadrivalent HPV (types
6, 11, 16, 18) recombinant vaccine that contains highly purified virus-like
particles.